Cuddy: Hai, House, you can has patient!!1 Her symptoms include this, that, and the other thing.
House: It's clearly brain cancer, stfu and leave me alone.
Cuddy: It can't be brain cancer! We did this test, and this test, and the other test!
House: (reads file, pops pills) Okay, me takey.
Dingbat Doctors: It's clearly tuberlosclerosis! Amyloidosis! Ramsay Hunt Syndrome! Russell-Silver syndrome! Guillain-Barré syndrome! Neurohydrofibrosystoexpealidocious!
EVERYBODY SING ALONG: IT. MUST. BE. LUPUS!!!111!1
(lots of tests later)
House: I don't know what it is, woe. Surely, she will die.
Wilson: Her name's not Shirley. You'd know this if, you know, you actually paid attention to your patient. Hey, have you found my keys?
House: .... the keys were hiding THE WHOLE TIME!!!111
Wilson: *wtf face*
House: (rushing into room): Waldenstrom’s macroglobulinemia!
Dingbat Doctors: But she's not fifty! And she's not male!
House: I'M TOTES RITE, YO, LOOK HERE.
Dingbat Doctors: Ohhhh.
QWP, but context is pissed she has to stay up late.