Ker-SCIENCE
SPIDEY: This threat is completely out of my league! I'd better go find the Avengers/Fantastic Four/Dr. Strange!
THREAT: Oh hell no. You're going down.
SPIDEY: Okay, so I can't kick your ass, but I'm too fast and smart for you to kick my ass.
THREAT: Goddammit!
SPIDEY: Ah ha! You've made a critical mistake!
[*KER-POW*!] or possibly [*KER-SCIENCE!*]
THREAT: X_X
SPIDEY: Bitch.
[TWO MONTHS LATER]
SPIDEY: This threat is completely out of my league! I'd better go find the Avengers/Fantastic Four/Dr. Strange!
THREAT: Oh hell no. You're going down.
Repeat until about 1991.
I think my favorite variations on that formula are the ones with this addition:
Avengers/Fantastic Four/Dr. Strange: Sorry we're late!
Spider-Man: Jeez, where were you guys?! I almost died!
Threat: X_X
A/FF/Dr. Strange: Um, okay. If you say so.
Context is nostalgic. And really has a point about that formula. (I'm gonna keep finding threads I like from